Regional differentiation of sympathetic activity during hypothalamic heating and cooling in anesthetized rabbits
Regional differentiation of sympathetic activity during hypothalamic heating and cooling in anesthetized rabbits
复制标题
麻醉兔下丘脑加热和冷却过程中交感神经活动的区域分化
DOI：
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发表时间：
2004
期刊：
影响因子：
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通讯作者：
E. Simon
中科院分区：
文献类型：
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作者：
M. Iriki;W. Riedel;E. Simon
SummaryIn anesthetized rabbits immobilized with succinyl choline, the discharges of sympathetic efferents supplying cutaneous and visceral regions were simultaneously recorded. The effects of thermal stimulation of the hypothalamic region were tested on the basis of the integrated discharges. During hypothalamic heating cutaneous sympathetic activity decreased, corresponding to increased ear blood flow, while visceral sympathetic activity increased. During hypothalamic cooling there was, on the average, no significant change of regional sympathetic activity. However, in single experimental periods an increase of cutaneous and a decrease of visceral sympathetic activity was found.The observed responses of regional sympathetic activity were compared with findings about regional cutaneous and intestinal blood flow under the same thermal stimulus and further with corresponding former investigations on regional blood flow and regional sympathetic activity during spinal thermal stimulation. It is suggested by this comparison that regional differentiation of sympathetic activity represents a specific thermoregulatory response of the vasomotor system mediated by the hypothalamic thermoregulatory center.
