PULMONARY PARAGONIMIASIS IN CAMEROON
PULMONARY PARAGONIMIASIS IN CAMEROON
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DOI：
10.1016/0035-9203(82)90102-x
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发表时间：
1982-01-01
影响因子：
2.2
通讯作者：
NCHINDA, TC
中科院分区：
文献类型：
--
作者：
KUM, PN;NCHINDA, TC
非洲并殖吸虫自 1952 年首次被描述以来，就被认为是喀麦隆 Meme 区巴科西地区的地方病。时隔 25 年，我们在该地区（但不是在同一村庄）开展了探索性工作，以研究该疾病的流行情况、记录常见症状、进行多次临床旁检查、评估人们对该疾病的信念和态度及其可能的原因。该病在该地区持续流行，并进行了 Niclofolan (Bilevon) 的治疗试验。发现该病的患病率为 5%，其中 20 岁以下人群的患病率较高。男孩比女孩受到的影响更大。人们似乎并没有认识到这种与结核病相混淆的疾病。这种疾病是通过食用未煮熟的中间宿主螃蟹而感染的。单剂量口服 Bilevon 的治疗试验完全成功。这项研究表明，在该地区结核病的鉴别诊断中必须认真考虑并殖吸虫病，并且需要进行更广泛的研究以确定该疾病的真实程度。
Paragonimus africanushas been known to be endemic in the Bakossi area of Meme Division of Cameroon since it was first described in 1952. After a lapse of 25 years, exploratory work was undertaken in the area (but not in the same villages) to study the prevalence of the disease, to record the common presenting symptoms, to make a number of paraclinical examinations, to assess the beliefs and attitudes of the people towards the disease and the possible reasons for its persistent endemicity in that area and to carry out a therapeutic trial with Niclofolan (Bilevon).The disease was found to have a prevalence of 5% with a higher prevalence among those less than 20 years old. Boys were more affected than girls. The population did not appear to recognize the disease which they confused with tuberculosis. The disease was contracted by eating improperly cooked crabs, the intermediate host. The therapeutic trial with Bilevon given orally as a single dose was completely successful. This study showed that paragonimiasis must be considered seriously in the differential diagnosis of tuberculosis in this area and that a study on a much wider scale is required to establish the real extent of the disease.