Tauroursodeoxycholic acid (TUDCA) in the prevention of total parenteral nutrition-associated liver disease

Tauroursodeoxycholic acid (TUDCA) in the prevention of total parenteral nutrition-associated liver disease
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DOI:
10.1067/mpd.2002.125802
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发表时间:
2002-08-01
影响因子:
5.1
通讯作者:
Rhodes, P
Rhodes, P
中科院分区:
医学2区
文献类型:
--
作者:
Heubi, JE;Wiechmann, DA;Rhodes, P

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目的:为了确定牛磺熊去氧胆酸(TUDCA)是否可以预防或改善全肠外营养(TPN)治疗的新生儿的肝损伤。
Objective: To determine whether tauroursodeoxycholic acid (TUDCA) would prevent or ameliorate the liver injury in neonates treated with total parenteral nutrition (TPN).Study design: Eligible infants were enrolled after surgery when serum direct bilirubin (DB) was