MicroRNA regulated defense responses in Triticum aestivum L. during Puccinia graminis f.sp tritici infection
MicroRNA regulated defense responses in Triticum aestivum L. during Puccinia graminis f.sp tritici infection
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DOI：
10.1007/s11033-011-0803-5
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发表时间：
2012-02-01
影响因子：
2.8
通讯作者：
Praveen, Shelly
中科院分区：
文献类型：
--
作者：
Gupta, Om Prakash;Permar, Vipin;Praveen, Shelly
植物已经进化出多种机制来识别病原体的攻击并触发防御反应。这些防御反应改变由内源性小的非编码mirna调节的宿主细胞功能。为了了解小麦茎锈病感染过程中miRNAs调控细胞功能的机制，我们研究了8种不同的miRNAs，即miR159、miR164、miR167、miR171、miR444、miR408、miR1129和miR1138，它们参与了3种不同的独立细胞防御反应。研究表明，在疾病开始时，mirna的积累可能在宿主的过敏反应（hypersensitive response， HR）中发挥关键作用，而在成熟阶段，这种反应会减弱。这表明一种可能的宿主-真菌协同关系导致易感性。这些miRNA在R基因存在和不存在时的差异表达可能解释了miRNA调控R基因介导的独立通路。
Plants have evolved diverse mechanism to recognize pathogen attack and triggers defense responses. These defense responses alter host cellular function regulated by endogenous, small, non-coding miRNAs. To understand the mechanism of miRNAs regulated cellular functions during stem rust infection in wheat, we investigated eight different miRNAs viz. miR159, miR164, miR167, miR171, miR444, miR408, miR1129 and miR1138, involved in three different independent cellular defense response to infection. The investigation reveals that at the initiation of disease, accumulation of miRNAs might be playing a key role in hypersensitive response (HR) from host, which diminishes at the maturation stage. This suggests a possible host-fungal synergistic relation leading to susceptibility. Differential expression of these miRNAs in presence and absence of R gene provides a probable explanation of miRNA regulated R gene mediated independent pathways.