Absence of evidence is not evidence of absence
Absence of evidence is not evidence of absence
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DOI：
10.1111/j.1751-0813.1996.tb13786.x
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发表时间：
1996-10-01
影响因子：
1.1
通讯作者：
Bland, JM
中科院分区：
文献类型：
--
作者：
Altman, DG;Bland, JM
DG ALI 'MAN和JM BLAND e统计学显著性和临床解释的非等效性仍然很常见。虽然在大型研究中，一个有意义的结果有时可能在临床上并不重要，但一个更大的问题来自对无意义结果的误解。按照惯例，P值大于5%（P> 0.05）被称为“不显著”。随机对照临床试验，没有显示出显着差异之间的治疗比较通常被称为“负面”。这个术语错误地暗示研究表明没有差异，而通常所显示的只是缺乏差异的证据。这是完全不同的说法
DG ALI ‘MAN and JM BLAND e non-equivalence of statistical significance and clinical interpretation remains common. Although a significant result in a large study may sometimes not be clinically important, a far greater problem arises from misinterpretation of non-significant findings. By convention a P value greater than 5%)(P> 0.05) is called ‘not significant’. Randomised controlled clinical trials that do not show a significant difference between the treatments being compared are often called ‘negative’. This term wrongly implies that the study has shown that there is no difference, whereas usually all that has been shown is an absence of evidence of a difference. These are quite different statements