Connections of Auditory and Visual Cortex in the Prairie Vole (Microtus ochrogaster): Evidence for Multisensory Processing in Primary Sensory Areas
Connections of Auditory and Visual Cortex in the Prairie Vole (Microtus ochrogaster): Evidence for Multisensory Processing in Primary Sensory Areas
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DOI：
10.1093/cercor/bhp082
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发表时间：
2010-01-01
期刊：
影响因子：
3.7
通讯作者：
Krubitzer, Leah
中科院分区：
文献类型：
--
作者：
Campi, Katharine L.;Bales, Karen L.;Krubitzer, Leah
在草原田鼠中，初级感觉区由对一种感觉方式做出反应的神经元主导，但一些神经元也对其他方式的刺激做出反应。为了揭示这些多模态反应的解剖学基础，我们检查了初级听觉区+前听觉区（A1 + AAF），颞前区（TA）和初级视觉区（V1）的连接。A1 + AAF与TA、多模态皮质（MM）、V1和初级躯体感觉区（S1）有内在联系和联系。TA与A1 + AAF、MM、V2有内在联系。胼胝体连接观察到的同伦位置在听觉皮层的两个领域。A1 + AAF和TA接受丘脑输入主要来自内侧膝状体核，但也来自外侧膝状体核（LGd），外侧后核和腹后核（VP）。V1与V2、MM、听觉皮质、梨状皮质（Pyr），在某些情况下，与体感皮质有密集的内在联系和联系。V1与V1、V2、MM、S1和Pyr有半球间联系，并接受来自LGd和VP的丘脑输入。我们的研究结果表明，多感觉整合发生在草原田鼠皮层的初级感觉区，这可能与其生态位相关的行为专业化。
In prairie voles, primary sensory areas are dominated by neurons that respond to one sensory modality, but some neurons also respond to stimulation of other modalities. To reveal the anatomical substrate for these multimodal responses, we examined the connections of the primary auditory area + the anterior auditory field (A1 + AAF), the temporal anterior area (TA), and the primary visual area (V1). A1 + AAF had intrinsic connections and connections with TA, multimodal cortex (MM), V1, and primary somatosensory area (S1). TA had intrinsic connections and connections with A1 + AAF, MM, and V2. Callosal connections were observed in homotopic locations in auditory cortex for both fields. A1 + AAF and TA receive thalamic input primarily from divisions of the medial geniculate nucleus but also from the lateral geniculate nucleus (LGd), the lateral posterior nucleus, and the ventral posterior nucleus (VP). V1 had dense intrinsic connections and connections with V2, MM, auditory cortex, pyriform cortex (Pyr), and, in some cases, somatosensory cortex. V1 had interhemispheric connections with V1, V2, MM, S1, and Pyr and received thalamic input from LGd and VP. Our results indicate that multisensory integration occurs in primary sensory areas of the prairie vole cortex, and this may be related to behavioral specializations associated with its niche.