Acute central thromboembolic disease: Posttherapeutic follow-up with spiral CT angiography
Acute central thromboembolic disease: Posttherapeutic follow-up with spiral CT angiography
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DOI：
10.1148/radiology.203.1.9122389
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发表时间：
1997-04-01
期刊：
影响因子：
19.7
通讯作者：
Duhamel, A
中科院分区：
文献类型：
--
作者：
RemyJardin, M;Louvegny, S;Duhamel, A
目的：评价急性中心性肺栓塞(PE)的治疗效果。材料与方法：62例经血管造影或螺旋CT诊断的急性中心性PE患者，平均11个月后行螺旋CT扫描。记录中央肺动脉水平未解决的急、慢性PE的CT征象。结果：在随访时，30例患者(组1，48%)急性PE完全缓解；32例(组2，52%)血管内异常(两组平均随访10.5个月)。虽然两组的临床表现、诊断时的危险因素和治疗方式没有统计学差异，但组2的急性PE比组1更广泛。在组2，CT显示24例急性PE未完全消退(2a组，39%)，8例慢性PE发展(2b组，13%)。6例患者有劳力性呼吸困难(2a组5例，2b组1例)，5例超声心动图显示肺动脉高压(均为2a组)。结论：螺旋CT可无创检测未解决的PE和新发的慢性PE。
PURPOSE: To evaluate the resolution of acute central pulmonary embolism (PE).MATERIALS AND METHODS: Sixty-two patients with angiographic (n = 43) or spiral computed tomographic (CT; n = 19) diagnosis of acute central PE underwent spiral CT after a mean of 11 months. CT signs of unresolved acute or chronic PE at the level of the central pulmonary arteries were recorded. A scoring system enabled quantification of endoluminal abnormalities at the time of diagnosis and follow-up.RESULTS: At follow-up, 30 patients (group 1; 48%) had complete resolution of acute PE; 32 patients (group 2; 52%) showed endovascular abnormalities (mean follow-up in both groups, 10.5 months). Whereas clinical presentation, risk factors at diagnosis, and therapeutic modalities did not differ statistically significantly between the two groups, group 2 had more extensive acute PE at diagnosis than did group 1. In group 2, CT showed an incomplete resolution of acute PE in 24 patients (group 2a; 39%) and development of chronic PE in eight patients (group 2b; 13%). Six patients had exertional dyspnea (five group 2a patients and one group 2b patient); five patients had echocardiographically demonstrated pulmonary hypertension (all group 2a patients).CONCLUSION: Spiral CT enabled noninvasive detection of unresolved PE and of newly developed chronic PE.