Birth weight, body mass index and asthma in young adults
Birth weight, body mass index and asthma in young adults
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DOI：
10.1136/thx.54.5.396
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发表时间：
1999-05-01
期刊：
影响因子：
10
通讯作者：
Azima, H
中科院分区：
文献类型：
--
作者：
Shaheen, SO;Sterne, JAC;Azima, H
背景-胎儿发育不良可能是哮喘的一个危险因素，尽管在儿童中的证据是相互矛盾的，在成人中的数据很少。对可能影响儿童晚期或成人早期哮喘的危险因素知之甚少。虽然有线索表明肥胖可能很重要，但这在年轻人中很少被研究。出生体重和儿童和成人的人体测量和哮喘，喘息，花粉热，湿疹之间的关系进行了调查，在一个全国性的代表性样本的年轻British adults. Methods-A共8960人从1970年英国队列研究（BCS 70）进行了研究。他们最近在26岁时回答了一份问卷，其中询问他们在过去的12个月内是否患有哮喘，喘息，花粉热和湿疹。成人的身体质量指数（BMI）计算报告的身高和weight.Results-The哮喘的患病率在26岁下降，随着出生体重的增加。在控制了潜在的混杂因素后，最低出生体重组（
Background-Impaired fetal growth may be a risk factor for asthma although evidence in children is conflicting and there are few data in adults. Little is known about risk factors which may influence asthma in late childhood or early adult Life. Whilst there are clues that fatness may be important, this has been little studied in young adults. The relations between birth weight and childhood and adult anthropometry and asthma, wheeze, hayfever, and eczema were investigated in a nationally representative sample of young British adults.Methods-A total of 8960 individuals from the 1970 British Cohort Study (BCS70) were studied. They had recently responded to a questionnaire at 26 years of age in which they were asked whether they had suffered from asthma, wheeze, hayfever, and eczema in the previous 12 months. Adult body mass index (BMI) was calculated from reported height and weight.Results-The prevalence of asthma at 26 years fell with increasing birth weight. After controlling for potential confounding factors, the odds ratio comparing the lowest birth weight group (