Risk factors for fractures of the wrist, shoulder and ankle: The Blue Mountains Eye Study

Risk factors for fractures of the wrist, shoulder and ankle: The Blue Mountains Eye Study
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DOI:
10.1007/s001980200063
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发表时间:
2002-01-01
影响因子:
4
通讯作者:
Peduto, AJ
Peduto, AJ
中科院分区:
医学2区
文献类型:
--
作者:
Ivers, RQ;Cumming, RG;Peduto, AJ

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很少有研究研究手腕、肩膀或脚踝骨折的危险因素。蓝山眼科研究是一项以人群为基础的纵向研究,对象是居住在澳大利亚悉尼以西地区的3654名年龄在49岁或以上的人。在基线(1992-3)和5年后(1997-9)进行了详细的眼科检查和面谈。通过自我报告和搜索医院放射学记录相结合的方法收集关于在随访期间持续的骨折的信息。经过4.7年的随访,受试者共发生了53处前臂远端骨折,20处肱骨近端骨折和33处脚踝骨折。在多因素模型中,与女性腕部骨折独立相关的因素是过去2周内未进行剧烈运动(相对危险度RR为0.4,95%可信区间为0.20~0.9)和曾经使用过HRT(相对危险度RR为0.4,95%可信区间为0.1~1.0)。与踝部骨折独立相关的因素有男性(RR 0.3,95%CI 0.1~0.8)和视野丧失(RR 2.8,95%CI 1.2~6.6)。这些发现与其他研究一致,并表明不同类型的骨质疏松性骨折具有不同的风险因素,如果有重叠的话。
Few studies have examined risk factors for fractures of the wrist, shoulder or ankle. The Blue Mountains Eye Study is a population-based longitudinal study in 3654 people aged 49 years or older resident in an area west of Sydney, Australia. Detailed eye examinations and interviews were carried out at baseline (1992-3) and after 5 years (1997-9). Information about fractures sustained during follow-up were collected by a combination of self-report and a search of hospital radiology records. After 4.7 years follow-up subjects had sustained 53 fractures of the distal forearm, 20 fractures of the proximal humerus and 33 ankle fractures. In multivariate models factors independently associated with wrist fractures in women were no vigorous exercise in the past 2 weeks (relative risk RR 0.4, 95% CI 0.20-0.9) and ever use of HRT (RR 0.4, 95% CI 0.1-1.0). Factors independently associated with ankle fractures were male sex (RR 0.3, 95% CI 0.1-0.8) and visual field loss (RR 2.8, 95% CI 1.2-6.6). These findings are in keeping with other studies, and suggest that different types of osteoporotic fracture have different, if overlapping, sets of risk factors.