Six month radiological and physiological outcomes in severe acute respiratory syndrome (SARS) survivors
Six month radiological and physiological outcomes in severe acute respiratory syndrome (SARS) survivors
复制标题
DOI：
10.1136/thx.2004.023762
复制
发表时间：
2004-10-01
期刊：
影响因子：
10
通讯作者：
Mok, TYW
中科院分区：
文献类型：
--
作者：
Ng, CK;Chan, JWM;Mok, TYW
背景资料：SARS幸存者和他们可能的决定因素的长期的生理和放射学结果是undetermined.Methods：SARS幸存者在一个区域医院的后续门诊进行了高分辨率计算机断层扫描（HRCT）的胸部和肺功能测试6个月后入院。的患者的临床和人口统计学数据和生理和放射学outcomes.Results之间的关联进行了检查：57例患者参加了这项研究。43例患者（75.4%）检测到肺功能异常，其中限制性缺陷（n = 16）最常见（28.1%）。43例患者（75.4%）检测到任何程度的放射学异常。只有使用脉冲皮质类固醇与CT异常的存在（P = 0.043，OR 6.65，95%CI 1.06至41.73）。结论：生理和放射学异常仍然存在于相当比例的SARS幸存者在6个月。
Background: The long term physiological and radiological outcomes of SARS survivors and their possible determinants are uncertain.Methods: SARS survivors in a follow up clinic in a regional hospital underwent high resolution computed tomography (HRCT) of the thorax and lung function tests 6 months after admission to hospital. The associations between the clinical and demographic data of the patients and the physiological and radiological outcomes were examined.Results: Fifty seven patients took part in the study. Lung function abnormalities were detected in 43 patients (75.4%), with restrictive defects (n = 16) being most common (28.1%). Radiological abnormalities of any degree were detected in 43 patients ( 75.4%). Only the use of pulse corticosteroids was associated with the presence of CT abnormalities ( p = 0.043, OR 6.65, 95% CI 1.06 to 41.73).Conclusions: Physiological and radiological abnormalities are still present in a considerable proportion of SARS survivors at 6 months.