Role of Synchronized Oscillatory Brain Activity for Human Pain Perception
Role of Synchronized Oscillatory Brain Activity for Human Pain Perception
复制标题
同步振荡大脑活动对人类疼痛感知的作用
DOI：
10.1515/revneuro.2008.19.6.441
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发表时间：
2008
影响因子：
4.1
通讯作者：
A. Engel
中科院分区：
文献类型：
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作者：
M. Hauck;J. Lorenz;A. Engel
自从现代神经成像技术的发展以来，对人类皮层疼痛处理的理解已经有了显着的提高。非侵入性的电生理方法，如脑电图和脑磁图已被证明是有用的工具，用于实时调查的神经元信号和皮层区域之间的同步通信。特别是，用这些技术记录的信号的时间-频率分解似乎是一种很有前途的方法，因为在不同的频带内可以观察到不同的疼痛相关的振荡变化，这可能与特定的感觉和运动功能有关。在这篇综述中，我们讨论了疼痛引起的时间-频率信号的最新证据，并提出振荡活动的变化反映了疼痛处理过程中调制的大脑中的一个重要通信机制。正常和病理性疼痛处理，如慢性疼痛状态的同步过程的重要性进行了讨论。
The understanding of cortical pain processing in humans has significantly improved since the development of modern neuroimaging techniques. Non-invasive electrophysiological approaches such as electro- and magnetoencephalography have proven to be helpful tools for the real-time investigation of neuronal signals and synchronous communication between cortical areas. In particular, time-frequency decomposition of signals recorded with these techniques seems to be a promising approach because different pain-related oscillatory changes can be observed within different frequency bands, which are likely to be linked to specific sensory and motor functions. In this review we discuss the latest evidence on pain-induced time-frequency signals and propose that changes in oscillatory activity reflect an essential communication mechanism in the brain that is modulated during pain processing. The importance of synchronization processes for normal and pathological pain processing, such as chronic pain states, is discussed.
影响因子：
--
作者：
K. Casey
通讯作者：
K. Casey