4-functionally substituted 3-heterylpyrazoles: III. 3-aryl(heteryl)pyrazole-4-carboxylic acids and their derivatives
4-functionally substituted 3-heterylpyrazoles: III. 3-aryl(heteryl)pyrazole-4-carboxylic acids and their derivatives
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DOI：
10.1023/a:1012490120976
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发表时间：
2001-04-01
影响因子：
0.8
通讯作者：
Vovk, MV
中科院分区：
文献类型：
--
作者：
Bratenko, MK;Chornous, VA;Vovk, MV
在水-吡啶介质中，3-芳基（杂基）-4-甲酰基吡唑被高锰酸钾彻底氧化，以高产率提供3-芳基（杂基）吡唑-4-羧酸，将其进一步转化为相应的氯化物和酰胺。
3-Aryl(heteryl)-4-formylpyrazoles were cleanly oxidized by potassium permanganate in water-pyridine medium to afford in high yield 3-aryl(heteryl)pyrazole-4-carboxylic acids, that were further converted into the corresponding chlorides and amides.