Displacement and strain imaging of coronary arteries with intraluminal ultrasound
Displacement and strain imaging of coronary arteries with intraluminal ultrasound
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DOI：
10.1109/58.485949
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发表时间：
1996-03-01
影响因子：
3.6
通讯作者：
ODonnell, M
中科院分区：
文献类型：
--
作者：
Shapo, BM;Crowe, JR;ODonnell, M
组织弹性可以通过在控制变形下获得的位移和应变图像来估计，我们将这种方法扩展到冠状动脉，通过集成血管成形术球囊和超声成像探头进行变形和成像。由于严重闭塞动脉的管腔横截面不是圆形的，我们还开发了一种技术，在管腔几何中心的参照系中执行所有运动计算。该坐标系统独立于成像导管，因此参考该框架消除了变形期间与球囊内探头运动相关的伪影，通过基于相敏相关的斑点跟踪估计的位移和应变用于区分模拟冠状动脉中不同弹性模量的动脉斑块：硬、软和均匀。我们还将这些方法应用于集成探针采集的均匀明胶幻影图像，最大幻影位移约为40 μ m，最大径向法向应变约为4%（绝对值），这些量的空间依赖性与理论预测值吻合良好。
Tissue elasticity can be estimated from displacement and strain images acquired under controlled deformation, We extend this approach for coronary arteries, deformed and imaged by an integrated angioplasty balloon and ultrasonic imaging probe. Because the lumen cross section of a severely occluded artery is not circular, we have also developed a technique to perform all motion computations in the reference frame of the lumen's geometric center. This coordinate system is independent of the imaging catheter and consequently referencing to this frame removes artifacts associated with probe motion within the balloon during deformation, Displacements and strains estimated by phase-sensitive correlation-based speckle tracking were used to distinguish arterial plaques in simulated coronary arteries of differing elastic moduli: hard, soft, and homogenous. We have also applied these methods to images of a homogeneous gelatin phantom collected with the integrated probe, The maximum phantom displacement was about 40 mu m, and the maximum radial normal strain was about 4% (absolute value), The spatial dependence of these quantities shows good agreement with theoretically predicted values.