Prevention of premature discontinuation of dual antiplatelet therapy in patients with coronary artery stents - A science advisory from the American Heart Association, American College of Cardiology, Society for Cardiovascular Angiography and Interventions, American College of Surgeons, and American Dental Association, with representation from the American College of Physicians
Prevention of premature discontinuation of dual antiplatelet therapy in patients with coronary artery stents - A science advisory from the American Heart Association, American College of Cardiology, Society for Cardiovascular Angiography and Interventions, American College of Surgeons, and American Dental Association, with representation from the American College of Physicians
复制标题
DOI：
10.1161/circulationaha.106.180944
复制
发表时间：
2007-02-13
期刊：
影响因子：
37.8
通讯作者：
Whitlow, Patrick
中科院分区：
文献类型：
--
作者：
Grines, Cindy L.;Bonow, Robert O.;Whitlow, Patrick
阿司匹林和噻吩并吡啶的双重抗血小板治疗已被证明可以减少冠状动脉支架术后的心脏事件。然而，许多患者和医疗保健提供者过早地停止双重抗血小板治疗，这大大增加了支架血栓形成、心肌梗死和死亡的风险。该咨询强调了在放置药物洗脱支架后12个月双重抗血小板治疗的重要性，并教育患者和医疗保健提供者有关过早停药的危害。它还建议将择期手术推迟1年，如果手术不能推迟，考虑在药物洗脱支架高危患者的围手术期继续使用阿司匹林。
Dual antiplatelet therapy with aspirin and a thienopyridine has been shown to reduce cardiac events after coronary stenting. However, many patients and healthcare providers prematurely discontinue dual antiplatelet therapy, which greatly increases the risk of stent thrombosis, myocardial infarction, and death. This advisory stresses the importance of 12 months of dual antiplatelet therapy after placement of a drug-eluting stent and educating the patient and healthcare providers about hazards of premature discontinuation. It also recommends postponing elective surgery for 1 year, and if surgery cannot be deferred, considering the continuation of aspirin during the perioperative period in high-risk patients with drug-eluting stents.