Drosophila melanogaster--the model organism of choice for the complex biology of multi-cellular organisms.
Drosophila melanogaster--the model organism of choice for the complex biology of multi-cellular organisms.
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发表时间：
2005-06
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通讯作者：
K. Beckingham;J. Armstrong;M. Texada;R. Munjaal;D. Baker
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作者：
K. Beckingham;J. Armstrong;M. Texada;R. Munjaal;D. Baker
近100年来，人们一直对黑腹果蝇（Drosophila melanogaster）进行深入研究。为分析这种生物体中的基因功能而发展的复杂的遗传和分子工具阵列是独一无二的。此外，果蝇是一种复杂的多细胞生物，其中许多发育和行为方面与人类相似。这些综合优势使果蝇的研究能够为理解基本生物学过程做出开创性贡献，并确保果蝇将继续在基因组时代提供独特的见解。这里给出了果蝇遗传学方法的概述，以及果蝇对我们理解细胞和有机体生物学的杰出贡献的例子。果蝇对我们的重力相关反应知识的贡献越来越大。
Drosophila melanogaster has been intensely studied for almost 100 years. The sophisticated array of genetic and molecular tools that have evolved for analysis of gene function in this organism are unique. Further, Drosophila is a complex multi-cellular organism in which many aspects of development and behavior parallel those in human beings. These combined advantages have permitted research in Drosophila to make seminal contributions to the understanding of fundamental biological processes and ensure that Drosophila will continue to provide unique insights in the genomic era. An overview of the genetic methodologies available in Drosophila is given here, together with examples of outstanding recent contributions of Drosophila to our understanding of cell and organismal biology. The growing contribution of Drosophila to our knowledge of gravity-related responses is addressed.