Medicinal products: Regulation of biosynthesis in space and time

Medicinal products: Regulation of biosynthesis in space and time
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DOI:
10.1590/s0074-02762000000100019
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发表时间:
2000-01-01
影响因子:
2.8
通讯作者:
Borin, MRD
Borin, MRD
中科院分区:
医学4区
文献类型:
--
作者:
Gottlieb, OR;Borin, MRD

文献摘要

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我们生活在一个“鬼魂出没的世界”。人类卫生保健要求病原体不断增加的耐药性面临着相应的快速发现新抗生素的速度。实现这一目标的可能策略之一涉及生物活性植物化学物质的合理定位。这种方法的概念基础在于令人惊讶的、鲜为人知的自然产品及其植物来源的形态、生态和进化,即对自然的一般机制的反思。
We live in a "Demon-Haunted World". Human health care rrquir es the ever increasing resistance of pathogens to be confronted by a correspondingly fast rate of discovery of novel antibiotics. One of the possible strategies towards this objective involves the rational localization of bioactive phytochemicals. The conceptual basis of the method consists in the surprisingly, little known gearings of natural products with morphology, ecology and evolution of their plant source, i.e. an introspection into the general mechanism of nature.