Early origin of sweet perception in the songbird radiation
Early origin of sweet perception in the songbird radiation
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鸣禽辐射中甜味感知的早期起源
DOI：
10.1126/science.abf6505
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发表时间：
2021
期刊：
影响因子：
56.9
通讯作者：
Buttemer
中科院分区：
文献类型：
--
作者：
Toda Yasuka;Ko Meng-Ching;Liang Qiaoyi;Miller Eliot T.;Rico-Guevara Alejandro;Nakagita Tomoya;Sakakibara Ayano;Uemura Kana;Sackton Timothy;Hayakawa Takashi;Sin Simon Yung Wa;Ishimaru Yoshiro;Misaka Takumi;Oteiza Pablo;Crall James;Edwards Scott V.;Buttemer
进化枝进化史上的早期事件可以塑造后代谱系的感觉系统。尽管鸟类祖先可能没有甜味受体，但以花蜜为食的鸟类的广泛发生表明它们多次获得糖检测。在这项研究中，我们发现了鲜味受体（T1R1-T1R3异二聚体）的一个早期感觉转变，它赋予鸣禽甜味感知能力，鸣禽是一种大型进化辐射，涵盖了所有现存鸟类的近一半。我们展示了不同饮食物种之间的糖反应，揭示了碳水化合物检测的关键位点，并确定了鸣禽和花蜜专家蜂鸟之间感觉趋同的分子基础。这种早期的转变塑造了整个辐射的感觉生物学，强调了偶然性的作用，并提供了鸟类进化中趋同的遗传基础的例子。
Early events in the evolutionary history of a clade can shape the sensory systems of descendant lineages. Although the avian ancestor may not have had a sweet receptor, the widespread incidence of nectar-feeding birds suggests multiple acquisitions of sugar detection. In this study, we identify a single early sensory shift of the umami receptor (the T1R1-T1R3 heterodimer) that conferred sweet-sensing abilities in songbirds, a large evolutionary radiation containing nearly half of all living birds. We demonstrate sugar responses across species with diverse diets, uncover critical sites underlying carbohydrate detection, and identify the molecular basis of sensory convergence between songbirds and nectar-specialist hummingbirds. This early shift shaped the sensory biology of an entire radiation, emphasizing the role of contingency and providing an example of the genetic basis of convergence in avian evolution.