Sense of life worth living (ikigai) and mortality in Japan: Ohsaki Study
Sense of life worth living (ikigai) and mortality in Japan: Ohsaki Study
复制标题
DOI：
10.1097/psy.0b013e31817e7e64
复制
发表时间：
2008-07-01
影响因子：
3.3
通讯作者：
Tsuji, Ichiro
中科院分区：
文献类型：
--
作者：
Sone, Toshimasa;Nakaya, Naoki;Tsuji, Ichiro
目的：探讨“生活价值感”与死因别死亡风险的关系。心理因素在发病和死亡风险中起重要作用。然而，消极心理因素与死亡风险之间的关系尚无定论。方法：Ohsaki研究是一项前瞻性队列研究，对43，391名日本成年人进行了研究。为了评估受试者是否找到了ikigai的感觉，他们被问到了这样一个问题：“你的生活中有ikigai吗？“我们使用考克斯回归分析来计算根据ikigai分类意义的全因和特定原因死亡率的风险比。结果：随访7年，3048例死亡。与发现有ikigai感的受试者相比，未发现ikigai感的受试者的全因死亡风险显著更高;多变量校正风险比（95%置信区间）为1.5（1.3-1.7）。至于死因特异性死亡率，没有发现ikigai的受试者与心血管疾病（1.6; 1.3-2.0）和外部原因死亡率（1.9; 1.1-3.3）的风险增加显著相关，但与癌症死亡率（1.3; 1.0-1.6）无关。结论：在这项前瞻性队列研究中，没有发现ikigai感的受试者与全因死亡风险增加相关。死亡风险的增加可归因于心血管疾病和外部原因，而不是癌症。
Objective: To investigate the association between the sense of "life worth living (ikigai)" and the cause-specific mortality risk. The psychological factors play important roles in morbidity and mortality risks. However, the association between the negative psychological factors and the risk of mortality is inconclusive. Methods: The Ohsaki Study, a prospective cohort study, was initiated on 43,391 Japanese adults. To assess if the subjects found a sense of ikigai, they were asked the question, "Do you have ikigai in your life?" We used Cox regression analysis to calculate the hazard ratio of the all-cause and cause-specific mortality according to the sense of ikigai categories. Results: Over 7 years' follow-up, 3048 of the subjects died. The risk of all-cause mortality was significantly higher among the subjects who did not find a sense of ikigai as compared with that in the subjects who found a sense of ikigai; the multivariate adjusted hazard ratio (95% confidence interval) was 1.5 (1.3-1.7). As for the cause-specific mortality, subjects who did not find a sense of ikigai were significantly associated with an increased risk of cardiovascular disease (1.6; 1.3-2.0) and external cause mortality (1.9; 1.1-3.3), but not of the cancer mortality (1.3; 1.0-1.6). Conclusions: In this prospective cohort study, subjects who did not find a sense of ikigai were associated with an increased risk of all-cause mortality. The increase in mortality risk was attributable to cardiovascular disease and external causes, but not cancer.