Neonatal Acute Kidney Injury
Neonatal Acute Kidney Injury
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DOI：
10.1542/peds.2014-3819
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发表时间：
2015-08-01
期刊：
影响因子：
8
通讯作者：
Kent, Alison L.
中科院分区：
文献类型：
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作者：
Selewski, David T.;Charlton, Jennifer R.;Kent, Alison L.
近年来，我们对急性肾损伤（AKI）及其对整个医学结果的影响的理解有了重大进展。基于单中心队列的研究表明，新生儿AKI非常常见，且与不良预后相关。在这篇最新的关于新生儿AKI的综述中，我们强调了新生儿肾生理、定义、危险因素、流行病学、结局、评估和处理的独特方面。肾功能随胎龄和实际年龄的变化。我们提出并描述了新生儿修改肾脏疾病：改善全球结局AKI标准，并为其作为新生儿AKI的标准化定义提供了基本原理。我们讨论了新生儿AKI的危险因素，并建议哪些患者群体需要更密切的监测，包括新生儿
In recent years, there have been significant advancements in our understanding of acute kidney injury (AKI) and its impact on outcomes across medicine. Research based on single-center cohorts suggests that neonatal AKI is very common and associated with poor outcomes. In this state-of-the-art review on neonatal AKI, we highlight the unique aspects of neonatal renal physiology, definition, risk factors, epidemiology, outcomes, evaluation, and management of AKI in neonates. The changes in renal function with gestational and chronologic age are described. We put forth and describe the neonatal modified Kidney Diseases: Improving Global Outcomes AKI criteria and provide the rationale for its use as the standardized definition of neonatal AKI. We discuss risk factors for neonatal AKI and suggest which patient populations may warrant closer surveillance, including neonates