Insomnia and Sleep-Related Breathing Disorders
Insomnia and Sleep-Related Breathing Disorders
复制标题
DOI：
10.1378/chest.09-1485
复制
发表时间：
2010-06-01
期刊：
影响因子：
9.6
通讯作者：
Collop, Nancy A.
中科院分区：
文献类型：
--
作者：
Wickwire, Emerson M.;Collop, Nancy A.
失眠症和阻塞性睡眠呼吸暂停是成年人中两种最常见的睡眠障碍。从历史上看，这些条件被概念化为正交，或者失眠被认为是睡眠呼吸暂停的症状。失眠研究人员试图排除有睡眠相关呼吸障碍（SRBD）风险的参与者，反之亦然。然而，近年来，人们越来越认识到失眠症和 SRBD 并存，并对这两种疾病同时发生时的患病率、后果和治疗产生了兴趣。尽管受到诊断标准和操作定义不一致的困扰，但临床和研究样本的证据一致表明这两种疾病之间的共病率很高。更重要的是，失眠症和 SRBD 具有累加的负面影响。迄今为止，只有少数研究探索了这些疾病的联合或序贯治疗。结果支持了睡眠医学综合、跨学科方法的重要性。本文回顾了迄今为止的实证文献，并提供了临床建议以及对未来研究的建议。胸部 2010； 137(6):1449-1463
Insomnia disorder and obstructive sleep apnea are the two most common sleep disorders among adults. Historically, these conditions have been conceptualized as orthogonal, or insomnia has been considered a symptom of sleep apnea. Insomnia researchers have sought to exclude participants at risk for sleep-related breathing disorders (SRBD), and vice versa. In recent years, however, there has been a growing recognition of co-occurring insomnia disorder and SRBD and interest in the prevalence, consequences, and treatment of the two conditions when they co-occur. Although plagued by inconsistent diagnostic criteria and operational definitions, evidence from clinical and research samples consistently suggests high rates of comorbidity between the two disorders. More important, insomnia disorder and SRBD have additive negative effects. To date, only a few studies have explored the combined or sequential treatment of the conditions. Results support the importance of an integrated, interdisciplinary approach to sleep medicine. This article reviews the empirical literature to date and provides clinical recommendations as well as suggestions for future research. CHEST 2010; 137(6):1449-1463