Rapid post-eruptive maturation of porcine enamel.
Rapid post-eruptive maturation of porcine enamel.
复制标题
DOI：
10.3389/fphys.2023.1099645
复制
发表时间：
2023
影响因子：
4
通讯作者：
中科院分区：
文献类型：
--
作者：
人类和猪的牙齿在大小、形状和牙釉质厚度上相似。人类乳切牙牙冠的形成大约需要 8 个月，而家猪的牙齿形成时间要短得多。仔猪在妊娠 115 天后出生，一些牙齿已萌出，断奶后必须满足其杂食性饮食的机械需求而不会失败。我们询问牙齿萌出前的短暂矿化时间是否与萌出后矿化过程相结合，该过程发生的速度有多快，以及萌出后牙釉质的硬化程度。为了解决这个问题，我们通过成分、微观结构和显微硬度分析，研究了猪出生后 2 周、4 周和 16 周（每个时间点 N = 3 只动物）的牙齿特性。我们收集了牙冠上三个标准化水平面的数据，以确定整个牙釉质厚度的特性变化以及与软组织萌出的关系。我们的研究结果表明，与健康的人类牙釉质相比，猪的牙齿萌出矿化程度较低，但在不到 4 周的时间内就达到了与健康人类牙釉质相似的硬度。
The teeth of humans and pigs are similar in size, shape, and enamel thickness. While the formation of human primary incisor crowns takes about 8 months, domestic pigs form their teeth within a much shorter time. Piglets are born after 115 days of gestation with some of their teeth erupted that must after weaning meet the mechanical demands of their omnivorous diet without failure. We asked whether this short mineralization time before tooth eruption is combined with a post-eruptive mineralization process, how fast this process occurs, and how much the enamel hardens after eruption. To address this question, we investigated the properties of porcine teeth at two, four, and sixteen weeks after birth (N = 3 animals per time point) through analyses of composition, microstructure, and microhardness. We collected data at three standardized horizontal planes across the tooth crown to determine the change of properties throughout the enamel thickness and in relation to soft tissue eruption. Our findings indicate that porcine teeth erupt hypomineralized compared to healthy human enamel and reach a hardness that is similar to healthy human enamel within less than 4 weeks.