NAAT-identified and self-reported gonorrhea and chlamydial infections: different at-risk population subgroups?
NAAT-identified and self-reported gonorrhea and chlamydial infections: different at-risk population subgroups?
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NAAT 识别和自我报告的淋病和衣原体感染：不同的高危人群亚组？
DOI：
10.1097/00007435-200210000-00005
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发表时间：
2002
影响因子：
3.1
通讯作者：
Turner,CharlesF
中科院分区：
文献类型：
--
作者：
Rogers,SusanM;Miller,HeatherG;Miller,WilliamC;Zenilman,JonathanM;Turner,CharlesF
关于淋病和衣原体感染高危人群的特征和行为的信息通常来自对性传播疾病（STD）门诊人群的研究。巴尔的摩性病和行为调查（BSBS）使用尿基核酸扩增检测（NAAT）来评估淋病和衣原体感染在马里兰州巴尔的摩市以人群为基础的横断面调查中的患病率和行为相关性。本研究的目的是研究自我报告有淋病和衣原体感染史的成年人报告的淋病和衣原体感染的人口统计学特征和行为标记，并将其与目前naat鉴定的淋病和衣原体感染个体的特征和行为进行比较。研究设计对居住在巴尔的摩的18至35岁的成年人进行概率抽样，收集尿液样本并进行健康和行为调查。数据和标本收集于1997年1月至1998年9月。结果被naat检测出淋病和/或衣原体感染的调查对象（7.9%）没有报告高危行为史或近期发生的高危行为，大多数无症状。然而，在我们的研究中，自我报告有感染史的成年人（26.0%）比没有感染史的成年人更有可能报告有多个性伴侣、有偿性行为、有性病病史的伴侣和有性病症状的伴侣——这一模式与之前基于临床的报告中描述的结果一致。结论：以症状性疾病为重点的临床人群研究得出的风险概况可能无法描述目前未经治疗且基本上无症状感染的更广泛人群。
Background Information on the characteristics and behaviors of persons at high risk for gonorrhea and chlamydial infection has typically been derived from studies of sexually transmitted disease (STD) clinic populations. The Baltimore STD and Behavior Survey (BSBS) used urine-based nucleic acid amplification testing (NAAT) to assess the prevalence and behavioral correlates of gonorrhea and chlamydial infection in a population-based cross-sectional survey of adults in Baltimore, Maryland.Goal The goal of this study was to examine the demographic characteristics and behavioral markers of gonorrhea and chlamydial infection as reported by adults with a self-reported history of gonorrhea and chlamydial infection and to compare these to the characteristics and behaviors of individuals with current NAAT-identified gonorrhea and/or chlamydial infection.Study Design A probability sample of adults aged 18 to 35 years residing in Baltimore was evaluated with collection of urine specimens and administration of a health and behavior survey. Data and specimens were collected between January 1997 and September 1998.Results Respondents with NAAT-detected gonorrhea and/or chlamydial infection (7.9%) did not report a history of high-risk behaviors or more recent occurrences of those behaviors, and the majority were asymptomatic. However, adults in our study who self-reported a history of infection (26.0%) were more likely than those with no history of infection to report multiple partners, paid sex, partners with prior STDs, and STD symptoms—a pattern consistent with findings described in previous clinic-based reports.Conclusion The risk profile generated from studies of clinic populations, with a focus on symptomatic disease, may not characterize the broader population with current, untreated, largely asymptomatic infection.