EXPLORATION AND SPATIAL-LEARNING IN STAGGERER MUTANT MICE

EXPLORATION AND SPATIAL-LEARNING IN STAGGERER MUTANT MICE
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DOI:
10.3109/01677068709102349
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发表时间:
1987-12-01
影响因子:
1.9
通讯作者:
LALONDE, R
LALONDE, R
中科院分区:
医学4区
文献类型:
--
作者:
LALONDE, R

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在自发交替和迷宫学习测试中对失去小脑浦肯野细胞和颗粒细胞以及下橄榄神经元的交错突变小鼠进行了评估。结果发现,与正常小鼠相反,交错突变体不会自发交替,并且在获得最大学习能力方面存在缺陷。据推测,橄榄小脑系统在视觉空间组织中发挥作用。
Staggerer mutant mice, that lose cerebellar Purkinje cells and granule cells and inferior olive neurons, were evaluated in tests of spontaneous alternation and maze learning. It was found that, contrary to normal mice, the staggerer mutants did not alternate spontaneously and had deficits in the acquisition of maxe learning. It is hypothesized that the olivocerebellar system has a role in visuo-spatial organization.