FAILURE OF SIGNS OF PHYSICAL-DEPENDENCE TO DEVELOP IN HAMSTERS AFTER PROLONGED CONSUMPTION OF LARGE DOSES OF ETHANOL
FAILURE OF SIGNS OF PHYSICAL-DEPENDENCE TO DEVELOP IN HAMSTERS AFTER PROLONGED CONSUMPTION OF LARGE DOSES OF ETHANOL
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DOI：
10.1016/0091-3057(77)90010-7
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发表时间：
1977-01-01
影响因子：
3.6
通讯作者：
PICK, JR
中科院分区：
文献类型：
--
作者：
MCMILLAN, DE;ELLIS, FW;PICK, JR
Male Golden Hamsters drank large amounts of ethanol with food and H2O freely available, when ethanol was presented in H2O at concentrations of 10-40% (wt/vol). Although the hamsters consumed an average of 13.8 g/kg per day of ethanol for 3 mo., no withdrawal signs were observed during 4 days without ethanol, nor were withdrawal signs observed during withdrawal after 4 more mo. of ethanol consumption. Although the Golden Hamster consumed large amounts of ethanol without the need for food or H2O deprivation, the Golden Hamsters may have limited usefulness as a model of physical dependence.
