NUMERICAL-SIMULATION OF ANNULAR-PHASED ARRAYS OF DIPOLES FOR HYPERTHERMIA OF DEEP-SEATED TUMORS
NUMERICAL-SIMULATION OF ANNULAR-PHASED ARRAYS OF DIPOLES FOR HYPERTHERMIA OF DEEP-SEATED TUMORS
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DOI：
10.1109/10.125005
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发表时间：
1992-03-01
影响因子：
4.6
通讯作者：
GANDHI, OP
中科院分区：
文献类型：
--
作者：
CHEN, JY;GANDHI, OP
我们已经使用了时域有限差分（FDTD）方法来计算SAR分布从一个环形相控阵的八个偶极天线耦合通过水“团”在解剖学为基础的三维模型的人体。我们评估了锥形团注腔室、频率（100-120 MHz）、偶极子长度（17-30 cm）以及各种偶极子的功率相位和振幅对在前列腺和肝脏的深部肿瘤区域聚焦能量的能力的影响。假设肿瘤的电导率和介电常数是类似的或略高于周围的正常组织，计算表明，所指出的参数的调整应导致在肿瘤承载区域的SAR分布的聚焦相当大的改善。如果这样的计算可以被证明是正确的预测经验测量从复杂的不均匀（虽然不一定解剖正确）幻影，他们可能是有用的热疗治疗计划的基础上，患者特定的解剖模型。
We have used the finite-difference time domain (FDTD) method to calculate the SAR distributions from an annular-phased array of eight dipole antennas coupled through water "boluses" in anatomically based three-dimensional models of the human body. We evaluated the effect of tapered bolus chambers, frequency (100-120 MHz), dipole length (17-30 cm), and phase and amplitude of power to the various dipoles on the ability to focus energy in the region of deep-seated tumors in the prostate and the liver. Assuming tumor conductivity and permittivity to be similar or slightly higher than surrounding normal tissues, calculations indicate that adjustment of the noted parameters should result in considerable improvement in focusing of SAR distributions in tumor-bearing regions. If such calculations can be shown to correctly predict empirical measurements from complex inhomogeneous (although not necessarily anatomically correct) phantoms, they may be useful for hyperthermia treatment planning based on patient-specific anatomic models.