The Prevalence of Peripheral and Central Hearing Impairment and Its Relation to Cognition in Older Adults
The Prevalence of Peripheral and Central Hearing Impairment and Its Relation to Cognition in Older Adults
复制标题
DOI：
10.1159/000371597
复制
发表时间：
2014-01-01
影响因子：
1.6
通讯作者：
Logroscino, Giancarlo
中科院分区：
文献类型：
--
作者：
Quaranta, Nicola;Coppola, Francesco;Logroscino, Giancarlo
年龄相关性听力损失(ARHL)和痴呆症是两种在成年人中非常普遍的疾病。最近的研究表明，听力损失与较差的认知功能独立相关。这项研究的目的是评估65岁以上受试者中ARHL和认知损害的患病率，并将听力功能与认知功能联系起来。作为多学科评估的一部分，参与Great Age研究的488名年龄超过65岁(平均年龄72.8岁)的受试者接受了完整的听力学、神经学和神经心理学评估。听力损失大于25dBHL的患病率为64.1%，中枢性听觉加工障碍(CAPD)的患病率为14.3%，25.3%的受试者在老年听力障碍筛查版问卷中报告有听力障碍。经性别、年龄和教育年限校正后的多元Logistic回归分析显示，轻度认知损害(MCI)与听力损害(CAPD和听力阈值；优势比1.6，p=0.05)显著相关；阿尔茨海默病(AD)与CAPD显著相关(优势比4.2，p=0.05)。鉴于受MCI影响的患者中高达80%转变为AD，在筛查认知电池中增加听觉测试可能对早期诊断认知能力下降有价值。(C)2015年S.Karger AG，巴塞尔
Age-related hearing loss (ARHL) and dementia are two highly prevalent conditions in the adult population. Recent studies have suggested that hearing loss is independently associated with poorer cognitive functioning. The aim of this study was to evaluate the prevalence of ARHL and cognitive impairment in a large sample of subjects older than 65 years and to correlate hearing function with cognitive function. A total of 488 subjects older than 65 years (mean age 72.8 years) participating in the Great Age Study underwent a complete audiological, neurological and neuropsychological evaluation as part of a multidisciplinary assessment. The prevalence of a hearing loss greater than 25 dB HL was 64.1%, of Central Auditory Processing Disorder (CAPD) was 14.3 and 25.3% of the subjects reported a hearing handicap as reported on the Hearing Handicap Inventory for the Elderly Screening Version questionnaire. Multiple logistic regression analysis corrected for gender, age and education duration showed that mild cognitive impairment (MCI) was significantly associated with hearing impairment (CAPD and hearing threshold; odds ratio 1.6, p = 0.05) and that Alzheimer's disease (AD) was significantly associated with CAPD (odds ratio 4.2, p = 0.05). Given that up to 80% of patients affected by MCI convert to AD, adding auditory tests to a screening cognitive battery might have value in the early diagnosis of cognitive decline. (C) 2015 S. Karger AG, Basel