Synergistic extraction of penicillin G with aliphatic alcohols and butyl acetate.
Synergistic extraction of penicillin G with aliphatic alcohols and butyl acetate.
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DOI：
10.1002/jctb.280610311
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发表时间：
1994-11
影响因子：
3.4
通讯作者：
Z. F. Yang;S. Yu;J. Y. Chen
中科院分区：
文献类型：
--
作者：
Z. F. Yang;S. Yu;J. Y. Chen
正己醇-乙酸丁酯混合溶剂已成功地用于青霉素G的萃取。该溶剂混合物不仅可以协同地和有效地提取青霉素G，而且还可以在从发酵液的滤液中提取青霉素G的过程中抑制乳液形成。通过化学分析和监测FT-IR光谱中官能团在溶剂中的吸收位移，研究了萃取平衡常数、萃取物中正己醇和青霉素G的摩尔比以及青霉素G的协同萃取。
A solvent mixture of 1-hexanol and butyl acetate has been successfully used for the extraction of penicillin G. This solvent mixture may not only synergistically and effectively extract penicillin G, but also inhibit emulsion formation during the extraction of penicillin G from the filtrate of the fermentation broth. The equilibrium constants of the extraction, the molar ratios of 1-hexanol and penicillin G in the extracted species and the synergistic extraction of penicillin G have been studied by chemical analysis and by monitoring the absorbency shift in the FT-IR spectra of the functional groups in the solvents.