Uveitis associated with scleritis.
Uveitis associated with scleritis.
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葡萄膜炎与巩膜炎有关。
DOI：
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发表时间：
1981
期刊：
影响因子：
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通讯作者：
A. Vasavada
中科院分区：
文献类型：
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作者：
K. Wilhelmus;P. Watson;A. Vasavada
在对350只眼睛的临床研究和对100只眼睛的组织病理学检查中，虹膜睫状体炎分别与巩膜炎和脉络膜炎相关，分别占42%和63%和12%和62%。临床、组织学和实验证据表明，硬化性葡萄膜炎开始于免疫反应的组合。在外来或自身抗原刺激后，宿主的个体免疫反应决定了巩膜肉芽肿性炎症和葡萄膜血管炎的存在、类型和程度。虹膜睫袢炎伴巩膜炎的存在提供了血管病变已扩展到眼球内部结构的推定证据，是进一步并发症和进行性视力丧失的不祥征兆。
In a clinical series of 350 eyes and a histopathological review of 100 globes, iridocyclitis was associated with scleritis in 42 and 63 per cent and choroiditis in 12 and 62 per cent respectively. Clinical, histological, and experimental evidence suggests that sclero-uveitis begins with a combination of immunological reactions. The host's individual immune response after foreign or self antigenic stimuli determines the presence, type, and extent of the scleral granulomatous inflammation and the uveal vasculitis. The presence of iridocyclitis accompanying scleritis offers presumptive evidence that a vasculitic process has extended to the inner structures of the globe and is an ominous sign of further complications and progressive visual loss.