Detection and localization of recent myocardial infarction by magnetic resonance imaging.
Detection and localization of recent myocardial infarction by magnetic resonance imaging.
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通过磁共振成像检测和定位近期心肌梗死。
DOI：
10.1016/0002-9149(86)90049-4
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发表时间：
1986
期刊：
影响因子：
--
通讯作者：
Parkey,RW
中科院分区：
文献类型：
--
作者：
Filipchuk,NG;Peshock,RM;Malloy,CR;Corbett,JR;Rehr,RB;Buja,LM;Jansen,DE;Redish,GR;Gabliani,GI;Parkey,RW
对27例平均间隔15天的急性心肌梗死（AMI）患者进行了磁共振成像（MRI）检测和定位的潜力评价。还对18名无症状志愿者进行了研究，以确定观察结果的特异性。AMI的诊断依据常规标准，所有患者均通过心电图定位梗死，19例通过焦磷酸锝造影定位梗死，1例通过尸检定位梗死。MRI显示88%的患者心肌信号增强，74%的患者出现空洞信号，67%的患者出现节段性室壁变薄。在每例患者的梗死区域中至少观察到这3个特征中的1个。这些MRI观察的灵敏度不受梗死位置或Q波存在的影响。无症状的志愿者也有83%的心肌信号增加，94%的空洞信号和11%的室壁变薄。一些患者在未怀疑近期或远期AMI累及的心肌节段出现这些结果。结果表明，平均在梗死后15天进行MRI检查可检出AMI。然而，正常志愿者的心脏和AMI患者表面正常的心肌节段可能具有先前与AMI相关的MRI表现。在这些发现中，室壁变薄是AMI最具预测性和特异性的。
The potential of magnetic resonance imaging (MRI) to detect and localize acute myocardial infarction (AMI) in 27 patients a mean interval of 15 days after AMI was evaluated. Eighteen asymptomatic volunteers were also studied to determine the specificity of the observations. The diagnosis of AMI was established by conventional criteria; the infarct was localized by electrocardiography in all patients, technetium pyrophosphate scintigraphy in 19 and necropsy in 1 patient. MRI detected increased myocardial signal intensity in 88%, cavitary signal in 74% and regional wall thinning in 67% of the patients. At least 1 of these 3 features was seen in the area of the infarct in each patient. The sensitivity of these MRI observations was not influenced by location of the infarct or presence of Q waves. Asymptomatic volunteers also had increased myocardial signal in 83%, cavitary signal in 94% and wall thinning in 11% of cases. Some patients had these findings in myocardial segments not suspected of being involved by recent or remote AMI. It is concluded that AMI can be detected by MRI performed an average of 15 days after infarction. However, the hearts of normal volunteers and apparently normal myocardial segments of patients with AMI may have the MRI findings previously associated with AMI. Of these findings, wall thinning was the most predictive of and specific for AMI.