Case-control study of risk factors for human infection with influenza A(H7N9) virus in Jiangsu Province, China, 2013
Case-control study of risk factors for human infection with influenza A(H7N9) virus in Jiangsu Province, China, 2013
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DOI：
10.2807/1560-7917.es2013.18.26.20510
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发表时间：
2013-06-27
期刊：
影响因子：
19
通讯作者：
Wang, H.
中科院分区：
文献类型：
--
作者：
Ai, J.;Huang, Y.;Wang, H.
我们描述了在中国江苏省进行的一项病例对照研究，以评估人类感染新型甲型禽流感（H7N9）病毒的危险因素。研究包括25例病例和93例按年龄、性别和地点匹配的对照。发病前两周内与家禽或禽类直接接触、慢性疾病（高血压除外）和环境相关暴露与甲型H7N9感染显著相关。自2013年2月在中国发现新出现的人感染H7N9禽流感病毒疫情以来，已引起全球公共卫生的严重关切。根据中国国家卫生和计划生育委员会的报告，截至2013年5月27日，中国大陆共报告了130例人间感染确诊病例，其中37例死亡（28%）。关于甲型H7N9禽流感病毒感染相关危险因素的描述性研究报道很少[1,2]。江苏省是新型甲型H7N9流感病毒最早出现的地区之一，我们开展了配对病例对照研究，以确定江苏省人感染甲型H7N9流感病例的潜在危险因素。
We describe a case-control study performed in Jiangsu, China, to evaluate risk factors for human infection with novel avian influenza A(H7N9) virus. Twenty-five cases and 93 controls matched by age, sex, and location were included in the study. Direct contact with poultry or birds in the two weeks before illness onset, chronic medical conditions (hypertension excluded), and environment-related exposures were significantly associated with A(H7N9) infection.Since it was discovered in February 2013, the emerging outbreak of human infections with a novel avian influenza A(H7N9) virus in China, has raised serious concerns for public health throughout the world [1]. According to reports by China National Health and Family Planning Commission, a total of 130 confirmed cases of human infection including 37 deaths (28%) were reported in mainland China as of 27 May 2013. Few descriptive studies have been reported on risk factors associated with avian influenza A(H7N9) virus infection [1,2]. We conducted a matched case-control study to identify potential risk factors for human influenza A(H7N9) cases in Jiangsu Province, one of the areas where the novel reassortant influenza A(H7N9) virus emerged earliest.