Role of microRNA in diabetic cardiomyopathy: From mechanism to intervention.
Role of microRNA in diabetic cardiomyopathy: From mechanism to intervention.
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DOI：
10.1016/j.bbadis.2017.03.013
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发表时间：
2017-08
期刊：
影响因子：
--
通讯作者：
Nair S
中科院分区：
文献类型：
--
作者：
Guo R;Nair S
Diabetic cardiomyopathy is a chronic and irreversible heart complication in diabetic patients, and is characterized by complex pathophysiologic events including early diastolic dysfunction, cardiac hypertrophy, ventricular dilation and systolic dysfunction, eventually resulting in heart failure. Despite these characteristics, the underlying mechanisms leading to diabetic cardiomyopathy are still elusive. Recent studies have implicated microRNA, a small and highly conserved non-coding RNA molecule, in the etiology of diabetes and its complications, suggesting a potentially novel approach for the diagnosis and treatment of diabetic cardiomyopathy. This brief review aims at capturing recent studies related to the role of microRNA in diabetic cardiomyopathy.
