Combination of Dual Wavelength Picosecond and Nanosecond Pulse Width Neodymium-Doped Yttrium-Aluminum-Garnet Lasers for Tattoo Removal
Combination of Dual Wavelength Picosecond and Nanosecond Pulse Width Neodymium-Doped Yttrium-Aluminum-Garnet Lasers for Tattoo Removal
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DOI：
10.1002/lsm.23181
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发表时间：
2019-11-14
影响因子：
2.4
通讯作者：
Uozumi, T.
中科院分区：
文献类型：
--
作者：
Kato, H.;Doi, K.;Uozumi, T.
背景与目的激光去除纹身主要采用脉冲宽度为纳秒级的调q激光。近年来，皮秒脉宽激光的治疗效果也有所报道。研究设计/材料和方法使用皮秒域掺钕钇铝石榴石激光器和磷酸钾钛基倍频晶体，我们进行了一项回顾性临床研究，采用脉冲宽度为750 ps和2 ns的联合治疗。将治疗次数与Kirby-Desai评分进行比较。在电子显微镜下比较2 ns和750 ps激光照射后的组织变化。结果脉冲宽度为2ns和750ps的联合治疗比调q掺钕钇铝石榴石激光治疗更安全有效。与Kirby-Desai评分相比，纹身去除的治疗次数明显减少，没有不良事件。扫描电镜结果表明，750毫安比2毫安更分散。结论脉冲宽度为2 ns和750 ps，波长为1064 nm和532 nm的掺钕钇铝石榴石激光联合治疗纹身安全有效，是一种有效的选择。激光外科医学(c) 2019 Wiley期刊，Inc。
Background and Objectives Tattoo removal by laser has been mostly performed using Q-switched laser, which has nanosecond pulse width. In recent years, the efficacy of treatment with picosecond pulse width laser has also been reported. Study Design/Materials and Methods Using a picosecond-domain, neodymium-doped yttrium-aluminum-garnet laser with a potassium-titanyl-phosphate frequency-doubling crystal, we performed a retrospective clinical study with combination treatment using pulse widths of 750 ps and 2 ns. The number of treatments was compared with the Kirby-Desai score. Tissue changes immediately after laser irradiation at 2 ns and 750 ps were compared using an electron microscope. Results The combination treatment using pulse widths of 2 ns and 750 ps was safe and more effective than the Q-switched neodymium-doped yttrium-aluminum-garnet laser treatment. Tattoo removal was possible with significantly fewer treatment numbers than the Kirby-Desai score, without adverse events. The results from the scanning electron microscope revealed that ink particles irradiated by 750 ps were more dispersed than those by 2 ns. Conclusions The combination treatment with pulse widths of 2 ns and 750 ps and 1064 nm and 532 nm wavelengths using the neodymium-doped yttrium-aluminum-garnet laser was safe and effective and can be a useful option for tattoo removal. Lasers Surg. Med. (c) 2019 Wiley Periodicals, Inc.