Ulysses - an application for the projection of molecular interactions across species
Ulysses - an application for the projection of molecular interactions across species
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DOI：
10.1186/gb-2005-6-12-r106
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发表时间：
2005-01-01
期刊：
影响因子：
12.3
通讯作者：
Ouellette, BFF
中科院分区：
文献类型：
--
作者：
Kemmer, D;Huang, Y;Ouellette, BFF
我们开发了一个面向用户的系统，它使用一个称为Interlog分析的过程来并行分析和显示在不同物种中检测到的蛋白质相互作用。该分析仪旨在通过将模式生物相互作用数据投影到同源人类蛋白质上来执行此类Interlog分析，因此可用作分析未表征人类蛋白质的加速器。对预测的相关性进行了评估，并根据已出版的参考资料集进行了验证。所有源代码都是免费提供的，并且可以通过Web界面http://www.cisreg.ca/ulysses访问该系统。
We developed Ulysses as a user-oriented system that uses a process called Interolog Analysis for the parallel analysis and display of protein interactions detected in various species. Ulysses was designed to perform such Interolog Analysis by the projection of model organism interaction data onto homologous human proteins, and thus serves as an accelerator for the analysis of uncharacterized human proteins. The relevance of projections was assessed and validated against published reference collections. All source code is freely available, and the Ulysses system can be accessed via a web interface http://www.cisreg.ca/ulysses.