Cellularity of developing subcutaneous adipose tissue in Landrace and Meishan pigs: Adipocyte size differences between two breeds
Cellularity of developing subcutaneous adipose tissue in Landrace and Meishan pigs: Adipocyte size differences between two breeds
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DOI：
10.1111/j.1740-0929.2010.00810.x
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发表时间：
2011-01-01
影响因子：
2
通讯作者：
Chikuni, Koichi
中科院分区：
文献类型：
--
作者：
Nakajima, Ikuyo;Oe, Mika;Chikuni, Koichi
实验旨在比较长白猪（低背膘）和梅山猪（高背膘）在 1 周、3 周、6 周、3 个月和 5 个月龄时皮下脂肪组织的脂肪细胞结构。随着猪的老龄化，两个品种的体重和背膘厚度均显着增加。与同龄比较时，调整至同等体重后，梅山猪的背膘厚度更大。脂肪细胞大小的平均直径也随着年龄的增长而增加，到6周时，梅山猪皮下脂肪组织外层和内层的脂肪细胞都更大。 5个月时，梅山猪约80%的脂肪组织质量归因于直径为95-165μm的脂肪细胞，而长白猪的大部分组织质量为75-145μm的脂肪细胞。尽管较小的脂肪细胞（25-45μm）对组织体积的贡献可以忽略不计，但两个品种在所有年龄段都显示出双相直径分布，表明脂肪细胞增生仍然活跃。我们的研究结果表明，长白猪和梅山猪的皮下脂肪组织之间存在细胞结构差异，脂肪细胞肥大是导致梅山猪背膘沉积较多的最主要因素。
Experiments were designed to compare the adipocyte cellularity of subcutaneous adipose tissue between growing Landrace (low backfat) and Meishan (high backfat) pigs at 1 week, 3 weeks, 6 weeks, 3 months and 5 months of age. As pigs aged, body weight and backfat thickness of both breeds significantly increased. When compared at equal ages, backfat thickness adjusted to equal body weight was greater for Meishan pigs. The mean diameter of fat cell size also increased with age, and by 6 weeks adipocytes from both outer and inner layers of subcutaneous adipose tissue were larger in Meishan pigs. At 5 months, approximately 80% of the adipose tissue mass in Meishan pigs was attributable to adipocytes measuring 95-165 mu m in diameter, whereas adipocytes of 75-145 mu m comprised most of the tissue mass in the Landrace. Although the contribution of smaller adipocytes (25-45 mu m) to the tissue volume was negligible, both breeds showed a biphasic diameter distribution at all ages, suggesting that adipocyte hyperplasia is still active. Our results demonstrate that cellularity differences exist between the subcutaneous adipose tissues of Landrace and Meishan pigs, and adipocyte hypertrophy is the most overwhelming contributor to the greater backfat deposition for Meishan pigs.