Disseminated Rhodococcus equi infection in two goats
Disseminated Rhodococcus equi infection in two goats
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DOI：
10.1354/vp.36-4-336
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发表时间：
1999-07-01
影响因子：
2.4
通讯作者：
Render, JA
中科院分区：
文献类型：
--
作者：
Davis, WP;Steficek, BA;Render, JA
同一群的两只山羊被诊断出马红球菌感染。尸检时，1号山羊的肝脏、肺、腹部淋巴结、右肱骨髓质、右侧第五肋骨和2号山羊的肝脏均散布大量干酪样肉芽肿。组织病理学检查证实这些器官中存在多发干酪样肉芽肿。在巨噬细胞的细胞质内鉴定出许多革兰氏阳性和吉姆萨阳性球杆菌。对两只山羊的肝脏和肺进行需氧细菌培养，得到了纯马R. 的生长。通过免疫组织化学方法在两只山羊的干酪肉芽肿中鉴定出马罗氏菌抗原。然而，未检测到马罗氏菌的 15 至 17 kd 毒力抗原，表明可能被该生物体的无毒株感染。
Rhodococcus equi infection was diagnosed in two goats from the same herd. At necropsy, numerous caseating granulomas were disseminated throughout the liver, lungs, abdominal lymph nodes, medulla of right humerus, and the right fifth rib of goat No. 1, and the liver of goat No. 2. Histopathologic examination confirmed the presence of multiple caseating granulomas in these organs. Numerous gram-positive and Giemsa-positive coccobacilli were identified within the cytoplasm of macrophages. Aerobic bacterial cultures of the liver and lung from both goats yielded a pure growth of R. equi. R. equi antigens were immunohistochemically identified in caseating,granulomas from both goats. However, the 15- to 17-kd virulence antigens of R. equi were not detected, suggesting possible infection by an avirulent strain of this organism.