AN EVALUATION OF THE GENOTOXIC PROPERTIES OF INSECTICIDES FOLLOWING PLANT AND ANIMAL ACTIVATION
AN EVALUATION OF THE GENOTOXIC PROPERTIES OF INSECTICIDES FOLLOWING PLANT AND ANIMAL ACTIVATION
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DOI：
10.1016/0165-1218(82)90161-6
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发表时间：
1982-01-01
期刊：
影响因子：
--
通讯作者：
PLEWA, MJ
中科院分区：
文献类型：
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作者：
GENTILE, JM;GENTILE, GJ;PLEWA, MJ
商业和技术等级的10种杀虫剂[环境污染物]的遗传毒性评价与鼠伤寒沙门氏菌和酿酒酵母菌直接和植物和动物激活后。还原位测试了每种杀虫剂的田间级制剂在玉米中蜡质（wx）位点的突变。克百威、毒死蜱、库拉克龙、威百亩和甲拌磷在所有检测中均为阴性。乙虫丙和特丁磷各有1次检测呈阳性，而百菌清、虫硫磷和七氯各有2次检测呈阳性。氟硫磷和特丁硫磷直接和动物活化后呈阳性，而百菌清和七氯在植物和动物活化后均呈阳性。百菌清、乙草胺、七氯在Z.梅斯[This研究可能适用于人类。
Commercial and technical grades of 10 insecticides [environmental pollutants] were evaluated for genotoxicity with Salmonella typhimurium and Saccharomyces cerevisiae directly and following plant and animal activation. Field-grade formulations of each insecticide were also tested for mutations at the waxy (wx) locus in Zea mays in situ. Carbofuran, chloropyrifos, curacron, metham and phorate were negative in all assays. Ethoprop and terbufos were each positive in 1 assay, and chlordane, fonofos and heptachlor were each positive in 2 assays. Fonofos and terbufos were positive directly and following animal activation while chlordane and heptachlor were positive following both plant and animal activation. Chlordane, ethoprop and heptachlor were positive in Z. mays. [This study may be applicable to humans.].