Human choriogonadotropin.
Human choriogonadotropin.
复制标题
人绒毛膜促性腺激素。
DOI：
10.1002/bies.950040207
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发表时间：
1986
期刊：
影响因子：
--
通讯作者：
Puett,D
中科院分区：
文献类型：
--
作者：
Puett,D
人绒毛膜促性腺激素是一种从胎盘的合体滋养细胞中提取的激素，是糖蛋白激素家族的一员，该家族还包括垂体激素、促卵泡激素和促甲状腺激素。这四种激素由两个不同的亚基组成，一个（α）是所有四种激素共同的，另一个（β）赋予激素特异性。关于这些亚基基因的性质和调控，以及这些复杂激素的结构、作用机制和生理作用的信息正在迅速积累。这篇小综述考虑了我们对人绒毛膜促性腺激素的理解的一些最新进展。
Human choriogonadotropin, a hormone derived from the syncytiotrophoblast cells of the placenta, is a member of the glycoprotein hormone family which also contains the pituitary hormones lutropin, follitropin and thyrotropin. These four hormones are comprised of two dissimilar subunits, one (α) being common to all four and the other (β) conferring hormonal specificity. Information is rapidly accumulating on the nature and regulation of the genes for these subunits, as well as the structural aspects, mechanism‐of‐action and physiological roles of these complex hormones. This mini review considers some of the recent advances in our understanding of human choriogonadotropin.