Maternal Parity, Fetal and Childhood Growth, and Cardiometabolic Risk Factors
Maternal Parity, Fetal and Childhood Growth, and Cardiometabolic Risk Factors
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DOI：
10.1161/hypertensionaha.114.03492
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发表时间：
2014-08-01
期刊：
影响因子：
8.3
通讯作者：
Jaddoe, Vincent W. V.
中科院分区：
文献类型：
--
作者：
Gaillard, Romy;Rurangirwa, Akashi A.;Jaddoe, Vincent W. V.
我们对9031名母亲及其子女进行了一项基于人群的前瞻性队列研究，研究了产妇胎次与胎儿和儿童生长特征以及儿童心脏代谢危险因素的关系。反复测量胎儿和儿童的生长情况。我们测量了儿童的人体测量、体脂分布、左心室质量、血压、血脂和6岁时的胰岛素水平。与未产母亲相比，多产母亲的孩子在妊娠晚期胎儿头围、身长和体重增长较高，早产和出生时胎龄小的风险较低，但出生时胎龄大的风险较高(P
We examined the associations of maternal parity with fetal and childhood growth characteristics and childhood cardiometabolic risk factors in a population-based prospective cohort study among 9031 mothers and their children. Fetal and childhood growth were repeatedly measured. We measured childhood anthropometrics, body fat distribution, left ventricular mass, blood pressure, blood lipids, and insulin levels at the age of 6 years. Compared with nulliparous mothers, multiparous mothers had children with higher third trimester fetal head circumference, length and weight growth, and lower risks of preterm birth and small-size-for-gestational-age at birth but a higher risk of large-size-for-gestational-age at birth (P