Enzyme-like catalysis by single chain nanoparticles that use transition metal cofactors
Enzyme-like catalysis by single chain nanoparticles that use transition metal cofactors
复制标题
使用过渡金属辅助因子的单链纳米粒子的类酶催化
DOI：
10.1039/d1cc05578j
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发表时间：
2022
影响因子：
4.9
通讯作者：
Zimmerman, Steven C.
中科院分区：
文献类型：
--
作者：
Xiong, Thao M.;Garcia, Edzna S.;Chen, Junfeng;Zhu, Lingyang;Alzona, Ariale J.;Zimmerman, Steven C.
我们报道了一种模块化的方法，在这种方法中，非共价交联的单链纳米颗粒(SCNP)选择性地结合催化剂的辅因子和底物，以提高铜催化的炔叠氮环加成反应的催化活性和Ru催化的氨基甲酸烯丙酯基团的裂解。
We report a modular approach in which a noncovalently cross-linked single chain nanoparticle (SCNP) selectively binds catalyst “cofactors” and substrates to increase both the catalytic activity of a Cu-catalyzed alkyne-azide cycloaddition reaction and the Ru-catalyzed cleavage of allylcarbamate groups compared to the free catalysts.