PLASMA-CHOLESTEROL AND TRIGLYCERIDE DISTRIBUTIONS IN 13,665 CHILDREN AND ADOLESCENTS - PREVALENCE STUDY OF THE LIPID RESEARCH CLINICS PROGRAM
PLASMA-CHOLESTEROL AND TRIGLYCERIDE DISTRIBUTIONS IN 13,665 CHILDREN AND ADOLESCENTS - PREVALENCE STUDY OF THE LIPID RESEARCH CLINICS PROGRAM
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DOI:
10.1203/00006450-198003000-00004
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发表时间:
1980-01-01
影响因子:
3.6
通讯作者:
RIFKIND, B
中科院分区:
文献类型:
--
作者:
CHRISTENSEN, B;GLUECK, C;RIFKIND, B
The age, race and sex specific distributions for plasma cholesterol (CH) and triglyceride (TG) are described for the 13,655 individuals under 20 yr old who were examined at the 1st visit (visit I) of the Prevalence Study of the Lipid Research Clinics (LRC) Program. Composite findings are presented from the 7 North American LRC where children were included in the target population. Cholesterol values are higher for blacks than for whites, but triglyceride values are higher for blacks than for whites, but triglyceride values are higher for whites than for blacks. In both the CH and TG distribututions for the combined races, the mean values for females are generally higher than for males. For cholesterol, consistent age-associated differences occur. On the average, the CH values peak in late childhood and decline during adolescence. The decrease in mean values for CH is most marked for white males. The values for TG tend to increase in early adolescence. The available information about lipid distributions in young populations is expanded and the extent of the variation in plasma lipids associated with race and sex for each age, 0-19 yr, is described. The pattern of age-associated differences found in these population-based, cross-sectional surveys suggests a need for prospective studies of lipid levels in cohorts examined before puberty and followed throughout adolescence and into early childhood. Such longitudinal studies may reveal the biological explanation for the age curve of the mean values for the age curve of the mean values for lipids, a risk factor for atherosclerotic cardiovascular disease.