Delayed osteotomy but not fracture healing in pediatric osteogenesis imperfecta patients receiving pamidronate
Delayed osteotomy but not fracture healing in pediatric osteogenesis imperfecta patients receiving pamidronate
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DOI：
10.1359/jbmr.040814
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发表时间：
2004-11-01
影响因子：
6.2
通讯作者：
Glorieux, FH
中科院分区：
文献类型：
--
作者：
Munns, CFJ;Rauch, F;Glorieux, FH
本研究评价了影响中重度OI儿童骨折（n = 197）和截骨术（n = 200）愈合的因素。帕米膦酸盐治疗与截骨术后延迟愈合有关，但与骨折后无关。这些数据表明，帕米膦酸盐和机械因素影响骨愈合在这个队列。
This study evaluated factors influencing fracture (n = 197) and osteotomy (n = 200) healing in children with moderate to severe OI. Pamidronate treatment was associated with delayed healing after osteotomy, but not after fracture. The data suggest that both pamidronate and mechanical factors influence bone healing in this cohort.