Cognitive behavioral therapy for psychogenic nonepileptic seizures

Cognitive behavioral therapy for psychogenic nonepileptic seizures
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DOI:
10.1016/j.yebeh.2009.02.016
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发表时间:
2009-04-01
影响因子:
2.6
通讯作者:
Keitner, Gabor I.
Keitner, Gabor I.
中科院分区:
医学3区
文献类型:
--
作者:
LaFrance, W. Curt, Jr.;Miller, Ivan W.;Keitner, Gabor I.

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尽管精神性非癫痫性发作(PNES)的患病率很高,且具有致残性,但其治疗试验却很少。我们评估了认知行为疗法(CBT)对减少PNES的影响。次要措施包括精神症状量表和心理社会变量。我们进行了一项前瞻性临床试验,评估使用PNES手册CBT治疗的门诊患者的PNES频率。被诊断患有视频/EEG证实的PNES的受试者接受了为期12周的PNES CBT治疗。前瞻性地绘制了癫痫发作日历。21例受试者入组,17例(81%)完成了CBT干预。17名完成者中有11名报告在最后一次CBT会议上没有癫痫发作。抑郁、焦虑、躯体症状、生活质量和心理社会功能量表的平均评分显示从基线到最后一次治疗的改善。认知行为疗法减少了PNES的数量,改善了精神症状和心理社会功能。和生活质量。(C)2009爱思唯尔公司版权所有
Treatment trials for psychogenic nonepileptic seizures (PNES) are few, despite the high prevalence and disabling nature of the disorder. We evaluated the effect of cognitive behavioral therapy (CBT) on reduction of PNES. Secondary measures included psychiatric symptom scales and psychosocial variables. We conducted a prospective clinical trial assessing the frequency of PNES in outpatients treated using a CBT for PNES manual. Subjects diagnosed with video/EEG-confirmed PNES were treated with CBT for PNES conducted in 12 weekly sessions. Seizure calendars were charted prospectively. Twenty-one subjects enrolled, and 17 (81%) completed the CBT intervention. Eleven of the 17 completers reported no seizures by their final CBT session. Mean scores on scales of depression, anxiety, somatic symptoms, quality of life, and psychosocial functioning showed improvement from baseline to final session. CBT for PNES reduced the number of PNES and improved psychiatric symptoms, psychosocial functioning. and quality of life. (C) 2009 Elsevier Inc. All rights reserved