The effects of sensory and parasympathetic denervation on the kinases and initiation factors controlling protein synthesis in the lacrimal gland.
The effects of sensory and parasympathetic denervation on the kinases and initiation factors controlling protein synthesis in the lacrimal gland.
复制标题
感觉和副交感神经去神经对控制泪腺蛋白质合成的激酶和起始因子的影响。
DOI：
10.1007/978-1-4615-0717-8_8
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发表时间：
2002
影响因子：
--
通讯作者：
Toshida,Hiroshi
中科院分区：
文献类型：
--
作者：
Nguyen,DoanH;Beuerman,RogerW;Toshida,Hiroshi
翻译主要在起始水平受到调控，由真核起始因子-4和-2复合物（eIF-4和eIF-2）介导。1,2 eIF-4复合体对于将mRNA招募到核糖体至关重要。这个综合体的两个最重要的组成部分是eIF-4E和eIF-4G。eIF-4E和eIF-4G的磷酸化增加了蛋白质合成以及特定信息的选择性翻译
Translation is regulated predominantly at the initiation level, mediated by the eukaryotic initiation factor-4 and -2 complexes (eIF-4 and eIF-2).1, 2The eIF-4 complex is essential for recruiting mRNA to a ribosome. The two most important components of this complex are the eIF-4E and eIF-4G. Phosphorylation of eIF-4E and eIF-4G increases protein synthesis as well as selective translation of specific messages.2