Microfluidics without pumps: reinventing the T-sensor and H-filter in paper networks.
Microfluidics without pumps: reinventing the T-sensor and H-filter in paper networks.
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DOI：
10.1039/c004821f
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发表时间：
2010-10-21
期刊：
影响因子：
6.1
通讯作者：
Yager P
中科院分区：
文献类型：
--
作者：
Osborn JL;Lutz B;Fu E;Kauffman P;Stevens DY;Yager P
传统的微流体装置通常需要高度精确的泵或气动控制系统，这增加了相当大的成本和对功率的需求。这些限制限制了微流体技术在护理点（POC）应用中的采用。纸网络提供了一种非常低成本和无泵的替代传统的微流体装置，通过产生流体输送通过毛细作用。我们重新审视了众所周知的流体动力学聚焦，基于大小的提取分子从复杂的混合物，微量混合和稀释的微流控设备，并证明纸基设备可以取代其昂贵的传统微流控同行。
Conventional microfluidic devices typically require highly precise pumps or pneumatic control systems, which add considerable cost and the requirement for power. These restrictions have limited the adoption of microfluidic technologies for point-of-care (POC) applications. Paper networks provide an extremely low-cost and pumpless alternative to conventional microfluidic devices by generating fluid tranport through capilarity. We revisit well-known microfluidic devices for hydrodynamic focusing, sized-based extraction of molecules from complex mixtures, micromixing, and dilution, and demonstrate that paper-based devices can replace their expensive conventional microfluidic counterparts.