Simple Way To Fabricate Novel Paper-Based Valves Using Plastic Comb Binding Spines
Simple Way To Fabricate Novel Paper-Based Valves Using Plastic Comb Binding Spines
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使用塑料梳装订刺制造新型纸基阀门的简单方法
DOI：
10.1021/acssensors.8b00518
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发表时间：
2018-09-01
期刊：
影响因子：
8.9
通讯作者：
Chen, Lingxin
中科院分区：
文献类型：
--
作者：
Han, Jinglong;Qi, Anjin;Chen, Lingxin
提出了一种在纸基微流控分析器件上制作纸基阀的新方法。3D mu PAD的初始原型操纵装置内流体的空间分布。在不同层中的可移动纸通道可以通过使用塑料梳状装订刺（PCBS）的通道的连接或断开来实现阀功能。整个阀门操作过程类似于一个台历，可以翻过来再翻回来。值得注意的是，这种PCBS阀可以在没有定时设置或任何触发器的情况下以简单且容易的方式控制流体，并且该优点使得未经训练的用户易于进行复杂且高通量的操作。可重复使用的塑料梳状结合刺大大降低了制造纸基阀的成本。为了评估性能，成功地分析了Fe（II）和亚硝酸盐的实际样品。我们希望这种方法能够为未来在μ PAD上制造纸质阀门引入一种新的方法。
A novel strategy for fabricating the paper-based valves on microfluidic paper-based analytical devices (mu PADs) was described to control fluid in a user-friendly way. Initial prototypes of 3D mu PADs manipulate the spatial distribution of fluid within the device. The movable paper channel in a different layer could be achieved using the channel's connection or disconnection to realize the valve function using plastic comb binding spines (PCBS). The entire valve manipulation process was similar to a desk calendar that can be flipped over and turned back. It is notable that this kind of PCBS valve can control a fluid in a simple and easy way without the timing setting or any trigger, and this advantage makes it user-friendly for untrained users to carry out the complex and high throughput operations. The reusable plastic comb binding spines greatly reduce the cost of fabricating paper-based valves. To evaluate the performance, the actual samples of Fe (II) and nitrite were successfully analyzed. We hope this method will introduce a new approach to fabrication of paper-based valves on mu PADs in the future.