Preparation of magnetically separable N-halamine nanocomposites for the improved antibacterial application
Preparation of magnetically separable N-halamine nanocomposites for the improved antibacterial application
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DOI：
10.1016/j.jcis.2011.08.036
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发表时间：
2011-12-15
影响因子：
9.9
通讯作者：
Chen, Yuxin
中科院分区：
文献类型：
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作者：
Dong, Alideertu;Lan, Shi;Chen, Yuxin
通过将磁性二氧化硅纳米颗粒包被抗菌n -卤胺聚合物，合成磁性n -卤胺纳米复合材料。采用透射电子显微镜（TEM）、动态光散射（DLS）、傅里叶变换红外（FTIR）、x射线衍射（XRD）、x射线光电子能谱（XPS）和热重分析（TGA）对合成的样品进行了表征。制备的磁性n -哈拉胺纳米复合材料对革兰氏阳性菌和革兰氏阴性菌的抗菌活性都比其块状材料强。研究了磁性n -卤胺纳米复合材料中氯含量对抗菌活性的影响。磁性N-halamine纳米复合材料还表现出超顺磁性，室温下饱和磁化强度为4.728 emu g(-1)，这使得这些纳米复合材料在抗菌行为之后具有磁性可分离性。磁性核与抗菌壳之间的协同作用表明，磁性N-halamine纳米复合材料可以用于抗菌应用，并且可以通过外磁场分离。(C) 2011爱思唯尔公司版权所有。
Magnetic N-halamine nanocomposites were synthesized through the encapsulation of the magnetic silica nanoparticles with antibacterial N-halamine polymer. The as-synthesized sample was characterized by transmission electron microscopy (TEM), dynamic light scattering (DLS), Fourier transform infrared (FTIR), X-ray diffraction (XRD), X-ray photoelectron spectra (XPS), and thermogravimetric analysis (TGA). The fabricated magnetic N-halamine nanocomposites possessed enhanced antibacterial activity against both Gram-positive and Gram-negative bacteria compared with their bulk counterparts. The effect of chlorine content of the magnetic N-halamine nanocomposites on the antibacterial activity was investigated. The magnetic N-halamine nanocomposites also exhibited super-paramagnetic behavior and had a saturation magnetization of 4.728 emu g(-1) at room temperature, which made these nanocomposites separable magnetically after the antibacterial behavior. Performances derived from the synergism between magnetic core and antibacterial shell suggest that the magnetic N-halamine nanocomposites are qualified for antibacterial applications and separable by the aid of the external magnetic field. (C) 2011 Elsevier Inc. All rights reserved.