Early Experience and Immunity
Early Experience and Immunity
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早期经验和免疫力
作者：
G. Solomon;S. Levine;John Kraft
成人生活中的许多生理和行为变量都与婴儿时期的经历有关。然而，婴儿刺激对免疫系统的影响还没有大规模的研究——这种影响可能对宿主抵抗传染病、癌症（鉴于越来越多的证据表明，对许多肿瘤的抵抗本质上是免疫的1,2）以及可能对自身免疫性疾病（可能与免疫功能不足的状态有关）产生重要影响。情绪和压力与感染、癌症和自身免疫疾病的发生和发展过程有关。我们现在已经研究了断奶前被抚摸过和没有被抚摸过的老鼠对鞭毛蛋白的不同免疫反应。
MANY physiological and behavioural variables in adult life have been related to infantile experience. There have, however, been no large scale studies of the effects of infantile stimulation on the immunological system—influences on which might have important implications in host resistance to infectious disease, to cancer (in view of growing evidence that resistance to many tumours is immunological in nature1,2) and possibly to auto-immune diseases, which may have an association with states of immunological insufficiency3. Emotions and stress have been related to the onset and course of infections, cancer and auto-immune diseases4, and we have now studied differential immunological responses to flagellin in rats handled and not handled before weaning.