Pertussis in infants, children, and adolescents: diagnosis, treatment, and prevention.
Pertussis in infants, children, and adolescents: diagnosis, treatment, and prevention.
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DOI：
10.1053/j.spid.2005.11.005
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发表时间：
2006-01-01
期刊：
影响因子：
--
通讯作者：
Munoz, Flor M
中科院分区：
文献类型：
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作者：
Munoz, Flor M
百日咳，又称百日咳，由革兰氏阴性多形性百日咳杆菌引起，是一种高度传染性、潜在威胁生命的呼吸道疾病，尽管接种率很高，但在全球范围内重新出现，成为婴儿、儿童和青少年大量发病和死亡的原因。提高认识和报告，除了有更好的诊断测试外，部分解释了最近百日咳的死灰复燃。然而，儿童免疫后免疫力的减弱导致了越来越多的易感青少年和成年人，他们能够将百日咳传播给脆弱的未接种或未完全接种疫苗的婴儿。美国和其他工业化国家建议为青少年使用无细胞百日咳疫苗增强剂。在百日咳的治疗中，主动免疫和早期诊断至关重要。
Pertussis, or "whooping cough," caused by the gram-negative pleomorphic bacillus Bordetella pertussis, is a highly contagious, potentially life-threatening respiratory tract illness that has re-emerged worldwide as a cause of substantial morbidity and mortality in infants, children, and adolescents, despite high vaccination rates. Increased awareness and reporting, in addition to the availability of better diagnostic tests, partially explain the recent resurgence of pertussis. However, waning immunity after childhood immunization has resulted in a growing pool of susceptible adolescents and adults who are capable of transmitting pertussis to vulnerable unvaccinated or incompletely vaccinated infants. An acellular pertussis vaccine booster for adolescents has been recommended in the United States and other industrialized countries. Active immunization and early diagnosis are crucial in the management of pertussis.