Effects of amobarbital and methohexital on epileptic activity in mesial temporal structures in epileptic patients. An EEG study with depth electrodes

Effects of amobarbital and methohexital on epileptic activity in mesial temporal structures in epileptic patients. An EEG study with depth electrodes
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异戊巴比妥和美索比妥对癫痫患者内侧颞叶结构癫痫活动的影响。

DOI:
10.1111/j.1600-0404.1984.tb00847.x
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发表时间:
1984
影响因子:
3.5
通讯作者:
B. Zetterlund
B. Zetterlund
中科院分区:
医学3区
文献类型:
--
作者:
J. Aasly;S. Blom;H. Silfvenius;B. Zetterlund

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摘要/ Abstract摘要:对30例耐药癫痫患者术前进行双侧潮汐内阿米妥(阿莫巴比妥)试验,评价其言语和记忆功能。其中8例(16例)患有部分复发性癫痫,采用双侧植入颞前内侧结构的深度电极记录脑电图。13个试验的脑电图均可定量测定脑电波活动。除一次试验外,在注射的同侧观察到尖峰频率的快速增加。无癫痫发作活动或临床发作。
Abstract– Bilateral intracarotidal Amytal (amobarbital) tests for evaluation of speech and memory function were performed during preoperative evaluation of 30 patients with drug‐resistant epilepsy. In 8 of these patients (16 tests), having partial complex epilepsy, EEG was recorded with depth electrodes, implanted bilaterally in anterior mesial temporal structures. The EEGs during 13 tests could be quantified with regard to spike activity. A rapid increase in spike frequency was observed ipsilateral to the injection in all tests but one. No seizure activity or clinical seizures were provoked.