Pt/C catalysed direct reductive amination of nitriles with primary amines in a continuous flow multichannel microreactor
Pt/C catalysed direct reductive amination of nitriles with primary amines in a continuous flow multichannel microreactor
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DOI：
10.1039/c2cy20431b
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发表时间：
2013-01-01
影响因子：
5
通讯作者：
Williams, Jonathan M. J.
中科院分区：
文献类型：
--
作者：
Sharma, Sumeet K.;Lynch, James;Williams, Jonathan M. J.
在连续流动多通道微反装置中，以铂/碳(质量分数为3%)为催化剂，通过一锅还原伯胺反应选择性合成了脂肪族和芳香族仲胺。在温和的反应条件下，使用分子氢作为清洁的还原剂。
Aliphatic and aromatic secondary amines were synthesised selectively by one pot reductive amination of nitriles with primary amines using Pt/C (3% by weight) catalyst in a continuous flow multichannel microreactor. Molecular hydrogen was used as a clean reducing agent at moderate reaction conditions.